Frontline Plus for dogs is a topical medication that works against tick and flea infestations. Its active ingredients, S-methoprene, and fipronil act to not only kill all existing ticks and fleas but also work on flea eggs and larvae to make sure that they do not mature into adults. This medication is known to have 100% efficacy within the first 48 hours of application. Apart from this, Frontline Plus is also preferred by many due to its long-lasting effect. Once applied, this medication can be effective for a whole month, even if you bathe your dog or take it for a swim. This is because fipronil accumulates in the animal’s sebaceous glands, from where it is consistently released onto the skin and coat. 
Frontline Plus for dogs is a safe medication to use and can be used on puppies and kittens as early as two days after birth. Although Frontline side effects are not common, they do at times occur and are mostly related to the alcohol that is used as a solvent.
Frontline Plus for Dogs Side Effects to Look For:
Common questions:
- Can Frontline make dogs sick?
- Can Frontline cause seizures in dogs?
- What are Frontline side effects?
- Is Frontline Plus safe for dogs?
If side effects occur following the use of Frontline Plus for dogs, they would generally be related to effects on the skin. There are also side effects that have at times been seen to be neurological or mental in nature.
Skin-Related Side Effects
An immediate reaction your dog could have following the application of the medication is skin irritation. Itching and hair loss at the site of application have also been reported in some dogs. Skin irritation usually manifests in the form of redness or skin discoloration and itching. Most often, the side effect is temporary and subsides in a few days. However, if the irritation does not subside or appears to be more severe than before, you should immediately consult your veterinarian.
When skin irritation occurs, your dog will try to scratch the area. This will aggravate the condition. So, keep an eye on your pet and prevent any scratching because scratching will lead to the medication spreading to their paws and other areas of their body, which they can lick. Scratching could also make the area bleed, which in turn would lead to the medication entering the bloodstream.
Neurologic Side Effects
Some of the neurologic side effects could include:
- Increased drooling
- Over-sensitivity to noise, light, or touch
- Becoming quiet and appearing depressed
- Aggression and anxiety
- Rapid heart rate
- Breathing or respiratory effects
- Panting and vomiting have also been seen in some dogs, although it passes quickly
If you see any of these symptoms persisting in your pet, consult your veterinarian immediately.
Frontline Plus for Dogs: Side Effects on Human and Other Species
Side effects on humans are rare. The most commonly reported effects are skin, mouth, and eye irritation. If this occurs, immediately wash the affected area with lots of clean water. The best way to avoid this effect is to apply Frontline Plus for dogs just before bedtime and allow the medication to completely dry overnight before cuddling the dog. Do not allow your dog to sleep in your bed after the application of the medication. Although severe reactions are extremely rare, a human being could experience vomiting, agitation, and seizures. If such effects occur, you should immediately consult your physician.
With regard to its effects on other species, the first thing to remember is DO NOT apply Frontline Plus for dogs on cats. There are flea treatments available specifically for cats. This medication could prove to be lethal for rabbits and aquatic species, so take adequate care to prevent such species from coming in contact with the medication.
Reviews of Frontline Plus for Dogs
- Didn’t work at allNoticed my dog had fleas about two weeks ago. Was recommended frontline plus by the lady in pet stock. The infestation is now worse I would say. It’s questionable whether this even made the slightest difference.
- Absolute waste of moneyI have applied Frontline Plus on my 2 German Shepherds 3 times now and it has made no difference at all. Time to try another product.
- ExcellentI bought Frontline Plus from BudgetPetCare after reading an extended review at buyfleatickmedicine and I tried it for 6 months on my dog. To be honest, my experience with Frontline Plus has been quite positive throughout this time. Initially I felt that it was not working but in first two months it vanished almost all my dog’s fleas and ticks. I still continued applying it for next four months and I am really glad that after that I had never needed to apply the Frontline Plus.
- Bad Product Frontline Plus false advertisingUsed frontline plus 2 days ago and still have fleas on my maltese.I am taking my 6 pack back to shop for a refund. Product is no good, do not buy Frontline Plus .Maker should be charged for false advertising and misleading the public under consumers law. I demand a full refund for a product that does not do what it is claimed to do ..
Source of the Reviews: Productreview.com
Natural Alternatives: Flea and Tick Protection Without the Chemicals
I totally get it—sometimes, the thought of putting chemicals on your dog just doesn’t sit right. If you’re one of those pet parents who’s looking for a more natural approach to flea and tick prevention, you’re not alone. Here are a few alternatives that might be worth considering.
Essential Oils: A Little Goes a Long Way
So, I’ve tried this myself—peppermint, lavender, and cedarwood oils, mixed with water, and spritzed lightly on my dog’s fur. Not only does it keep the bugs away, but it also makes them smell like they’ve just come back from a spa day. Just be sure to dilute the oils properly—too much can irritate their skin.
Apple Cider Vinegar: Your Kitchen’s Secret Weapon
Who knew apple cider vinegar could be a flea-fighting superhero? I mix it with water, spray it on my dog, and boom—no fleas! It’s super cheap and works wonders, but make sure to test a small patch first just to be safe.
Diatomaceous Earth: Nature’s Bug Buster
This one’s a little less well-known, but I’ve heard great things about diatomaceous earth (DE). You sprinkle it lightly on your dog’s fur and around the house, and it’s said to help kill fleas by drying them out. It’s all-natural and harmless to pets, but I always make sure not to let my dog inhale it. Safety first!
Herbal Flea Collars: A Natural, Ongoing Solution
For a hands-off option, herbal flea collars can be a game-changer. They’re infused with essential oils and offer a steady defense against fleas and ticks. I love how simple it is—just put it on and forget about it (until it’s time for a replacement, of course).
Neurological Side Effects: What to Watch For
Although rare, some dogs can have neurological reactions to Frontline. It’s important to recognize the signs, especially if you notice anything unusual in your dog after applying the treatment. Here’s what to look for and what you should do if you spot these symptoms.
Twitching and Shaking
If your dog starts twitching or shaking, especially their muscles or legs, it’s not just a case of excitement or being cold. This kind of muscle jerking could be a sign of a neurological reaction to Frontline.
What to do?
If you notice twitching, stop using Frontline right away. It’s crucial to call your vet as soon as possible. They’ll want to know when you applied the product and the exact symptoms your dog is showing.
Seizures: A Major Red Flag
Seizures are one of the most alarming neurological side effects. If your dog suddenly collapses, starts convulsing, or loses control of their body, it can be terrifying. They may foam at the mouth, have their eyes roll back, or jerk uncontrollably.
What to do?
If your dog has a seizure, don’t wait around. Call your vet immediately. If the seizure lasts more than a couple of minutes, head to the vet right away. Even if it’s a short seizure, it’s always best to have your dog evaluated by a professional.
Disorientation and Odd Behavior
Another sign of a neurological issue is when your dog starts acting disoriented—walking in circles, bumping into things, or looking confused. This could be a result of Frontline affecting their nervous system.
What to do?
If you notice your dog acting disoriented, keep them in a safe space, away from stairs or hazards. Call your vet to discuss the symptoms and get advice on the next steps.
Source by Dan Banks
